This website uses cookies to improve your experience while you navigate through the website. It does not store any personal data. Designated as one of the best colleges by Colleges of Distinction. CSHL researchers began studying sarcoma in 2014, thanks in part to the encouragement and investments of three local foundations. This cookie is set by GDPR Cookie Consent plugin. Assembly of a complex containing Cdc45p, replication protein A, and Mcm2p at replication origins controlled by S-phase cyclin-dependent kinases and Cdc7p-Dbf4p kinase. Once you've found the features that suit you, stop in to see us or open an account online today. How one family secured the future of a laboratory, Business Development & Technology Transfer, Center for Humanities & History of Modern Biology, CSHL and Hofstra Northwell Health Clinical and Translational Fellowship, Summer Research Internship for Medical Students, CSHL President Bruce Stillman wins Heineken Prize, American Association for Cancer Research, Elected Fellow of the AACR Academy, Herbert Tabor Research Award, American Society for Biochemistry and Molecular Biology, Louisa Gross Horwitz Prize, Columbia University, American Academy of Arts and Sciences, Elected Member, Curtin Medal for Excellence in Medical Research, Australian National University, Alfred P. Sloan Prize, General Motors Cancer Research Foundation, National Academy of Sciences, Elected Foreign Associate, The structure of ORCCdc6 on an origin DNA reveals the mechanism of ORC activation by the replication initiator Cdc6. Stillman Trust & Wealth Management offers a full range of trust & investment services to individuals and businesses. After we're done with this case, I'm giving you Neil, , , , He kidnapped an investigative journalist because he wanted Albert, - , , It might not be money, but there's definitely something Harlan has that, , , -, , , . CSHL President & CEO Bruce Stillman explained the importance of genetics education. )) . The Long Island Herald recognized CSHL President and CEO Bruce Stillman for his leadership and impact in the biomedical field. Fast, easy, and safe! Advertisement cookies are used to provide visitors with relevant ads and marketing campaigns. Increasing gender diversity in the STEM research workforce. , . These mutations have been linked to MeierGorlin syndrome, a condition that results in people with extreme dwarfism and small brain size, but normal intelligence. CSHL and CUNY opened a new DNA Learning Center in Brooklyn, NY. The dynamic nature of the human origin recognition complex revealed through five cryoEM structures, The dynamic nature of the human Origin Recognition Complex revealed through five cryoEM structures, The human Origin Recognition Complex is essential for pre-RC assembly, mitosis and maintenance of nuclear structure, Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6, Evolution of DNA Replication Origin Specification and Gene Silencing Mechanisms. info@cshl.edu
All Rights Reserved. (13 PART D) | :173 Smith, S, Stillman, B, 20 Dec 1988 | Biochimica et Biophysica Acta: international journal of biochemistry and biophysics | 951(2-3):382-7 Fairman, M, Prelich, G, Tsurimoto, T, Stillman, B, Apr 1988 | Proceedings of the National Academy of Sciences of USA | 85(7):2120-4 Diffley, J, Stillman, B, 8 Apr 1988 | Cell | 53(1):117-26 Prelich, G, Stillman, B, Sep 1988 | Journal of Virology | 62(9):3445-54 White, E, Denton, A, Stillman, B, Apr 1988 | The EMBO Journal | 7(4):1211-8 Fairman, M, Stillman, B, Aug 1988 | BioEssays | 9(2-3):56-60 Stillman, B, May 1988 | Molecular and Cellular Biology | 8(5):1923-1931 Heintz, N, Stillman, B, 15 Dec 1987 | Philosophical Transactions of the Royal Society B: Biological Sciences | 317(1187):495-505 Fairman, M, Prelich, G, Stillman, B, 2 Apr 1987 | Nature | 326(6112):517-20 Prelich, G, Tan, C, Kostura, M, Mathews, M, So, A, Downey, K, Stillman, B, 2 Apr 1987 | Nature | 326(6112):471-475 Prelich, G, Kostura, M, Marshak, D, Mathews, M, Stillman, B, 1987 | Journal of Cellular Biochemistry | 35(S11C):152 White, E, Denton, A, Stillman, B, Jan 1987 | The EMBO Journal | 6(1):153-60 Mohr, I, Stillman, B, Gluzman, Y, Feb 1987 | Journal of Virology | 61(2):426-35 White, E, Stillman, B, Nov 1986 | Proceedings of the National Academy of Sciences of USA | 83(22):8550-8554 Ostapchuk, P, Diffley, J, Bruder, J, Stillman, B, Levine, A, Hearing, P, 1986 | Cancer surveys | 5(2):389-404 Stillman, B, Nov 1986 | Molecular and Cellular Biology | 6(11):3763-3773 White, E, Faha, B, Stillman, B, 23 May 1986 | Cell | 45(4):555-65 Stillman, B, 1986 | Journal of Cellular Biochemistry | 32(S10B):229 Diffley, J, Stillman, B, Mar 1986 | Journal of Virology | 57(3):883-892 Prelich, G, Stillman, B, May 1986 | Molecular and Cellular Biology | 6(5):1363-73 Diffley, J, Stillman, B, 1985 | Molecular and Cellular Biology | 5(8):2051-2060 Stillman, B, Gluzman, Y, 1985 | The EMBO Journal | 4(11):2933-2939 Stillman, B, Gerard, R, Guggenheimer, R, Gluzman, Y, 1983 | Current Topics in Microbiology and Immunology | 109:75-87 Tamanoi, F, Stillman, B, Doerfler, Walter, 1984 | Proceedings of the National Academy of Sciences of USA | 81(10):3069-3073 Guggenheimer, R, Stillman, B, Nagata, K, Tamanoi, F, Hurwitz, J, 1984 | Journal of Virology | 52(2):410-419 White, E, Grodzicker, T, Stillman, B, 1984 | Journal of Virology | 50(2):598-605 Stillman, B, White, E, Grodzicker, T, 1984 | Molecular and Cellular Biology | 4(12):2865-2875 White, E, Blose, S, Stillman, B, 1984 | Current Topics in Microbiology and Immunology | 109:75-87 Tamanoi, F, Stillman, B, 1983 | Journal of Cellular Biochemistry | 21(S7A):130 Stillman, B, Tamanoi, F, Nov 1983 | Proceedings of the National Academy of Sciences of USA | 80(21):6446-50 Tamanoi, F, Stillman, B, 1983 | Cold Spring Harbor Laboratory: Symposia on Quantitative Biology | 47(2):741-750 Stillman, B, Tamanoi, F, 1982 | Journal of Biological Chemistry | 257(22):13499-13506 Smart, J, Stillman, B, Dec 1982 | Cell | 31(3 Pt 2):613-23 Stillman, B, Tamanoi, F, Mathews, M, Apr 1982 | Proceedings of the National Academy of Sciences of USA | 79(7):2221-2225 Tamanoi, F, Stillman, B, Nov 1982 | Journal of Virology | 44(2):530-7 Stillman, B, Topp, W, Engler, J, 1983 | Cold Spring Harbor Laboratory: Symposia on Quantitative Biology | 47 Pt 2:741-750 Stillman, B, Tamanoi, F, 1981 | Cell | 23(2):497-508 Stillman, B, Lewis, J, Chow, L, Mathews, M, Smart, J, 1981 | Journal of Virology | 37(1):139-147 Stillman, B, 1980 | Journal of supramolecular structure | 14(S4):260 Mathews, M, Esche, H, Smart, J, Stillman, B, Harter, M, Lewis, J, 1979 | Cold Spring Harbor Laboratory: Symposia on Quantitative Biology | 44(1):493-508 Lewis, J, Esche, H, Smart, J, Stillman, B, Harter, M, Mathews, M, 1979 | Cold Spring Harbor Laboratory: Symposia on Quantitative Biology | 43(2):729-739 Stillman, B, Bellett, A, Feb 1979 | Virology | 93(1):69-79 Stillman, B, Bellett, A, 20 Oct 1977 | Nature | 269(5630):723-5 Stillman, B, Bellett, A, Robinson, A, Faculty & Staff Faculty Awards CSHL-Northwell Health Affiliation, Cancer Center Neuroscience Genomics Quantitative Biology Plant Biology, CSHL Fellows Program Postdoctoral Research Graduate Program Career Development Translational Training, Core Facilities Sponsored Programs/Grants Uplands Farm Research Computing Meetings & Courses Program Library & Archives, 516-367-8800
Functional cookies help to perform certain functionalities like sharing the content of the website on social media platforms, collect feedbacks, and other third-party features. This cookie is set by GDPR Cookie Consent plugin. CSHL President and CEO Bruce Stillman received the prestigious 2021 Australian Advance Global Impact Award. This cookie is set by GDPR Cookie Consent plugin. Other uncategorized cookies are those that are being analyzed and have not been classified into a category as yet. By clicking "continue" or by continuing to use our website, you are agreeing to our use of cookies as detailed in our. . Cold Spring Harbor Laboratory and the City University of New York announce the opening of the DNA Learning Center NYC at City Tech. 2022 Cold Spring Harbor Laboratory. Assembly of a complex containing Cdc45p, replication protein A, and Mcm2p at replication origins controlled by S-phase cyclin-dependent kinases and Cdc7p-Dbf4p kinase, A double-hexamer archaeal minichromosome maintenance protein is an ATP-dependent DNA helicase, Yeast autonomously replicating sequence binding factor is involved in nucleotide excision repair, Cdc7p-Dbf4p kinase binds to chromatin during S phase and is regulated by both the APC and the RAD53 checkpoint pathway, Histone acetyltransferase HBO1 interacts with the ORC1 subunit of the human initiator protein, Replication-dependent marking of DNA by PCNA facilitates CAF-1-coupled inheritance of chromatin, The Cdc6p nucleotide-binding motif is required for loading mcm proteins onto chromatin, Heterochromatin Dynamics in Mouse Cells: Interaction between Chromatin Assembly Factor 1 and HP1 Proteins, The Orc4p and Orc5p Subunits of the Xenopus and Human Origin Recognition Complex Are Related to Orc1p and Cdc6p, The DNA replication fork in eukaryotic cells, Formation of a preinitiation complex by S-phase cyclin CDK-dependent loading of Cdc45p onto chromatin, Cdc6 is regulated by E2F and is essential for DNA replication in mammalian cells, Reconstitution of recombinant human replication factor C (RFC) and identification of an RFC subcomplex possessing DNA-dependent ATPase activity, Nucleosomal DNA regulates the core-histone-binding subunit of the human Hat1 acetyltransferase, Persistent initiation of DNA replication and chromatin-bound MCM proteins during the cell cycle in cdc6 mutants, Inhibition of CDK activity and PCNA-dependent DNA replication by p21 is blocked by interaction with the HPV-16 E7oncoprotein, Ultraviolet radiation sensitivity and reduction of telomeric silencing in Saccharomyces cerevisiae cells lacking chromatin assembly factor-I, p62(dok): a constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells, Nucleosome assembly by a complex of CAF-1 and acetylated histones H3/H4, Chromatin assembly coupled to DNA repair: a new role for chromatin assembly factor I, Simian virus 40 large T antigen binds to topoisomerase I, Subcellular distribution of p21 and PCNA in normal and repair-deficient cells following DNA damage, The multidomain structure of Orc1p reveals similarity to regulators of DNA replication and transcriptional silencing, The p150 and p60 subunits of chromatin assembly factor I: a molecular link between newly synthesized histones and DNA replication, ORC and Cdc6p interact and determine the frequency of initiation of DNA replication in the genome, Identification of eukaryotic DNA replication proteins using simian virus 40 in vitro replication system, Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair, Smart machines at the DNA replication fork, The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA, Anatomy of a DNA replication fork revealed by reconstitution of SV40 DNA replication in vitro, Coordination of Transcription and Pre-Messenger-Rna Splicing within the Cell-Nucleus, Functional conservation of multiple elements in yeast chromosomal replicators, Cloning, Expression, and Chromosomal Localization of the 140-Kilodalton Subunit of Replication Factor-C from Mice and Humans, Chromosomes and expression mechanisms: Editorial overview, Simian virus 40 origin- and T-antigen-dependent DNA replication with Drosophila factors in vitro, 59Th Cold-Spring-Harbor Symposium On Quantitative Biology - The Molecular Genetics Of Cancer - Foreword, Initiation of Virus and Cell-DNA Replication, Analysis of a protein-binding domain of p53, The replicon model and eukaryotic chromosomes, The DNA-Binding Domain of Simian Virus-40 Tumor-Antigen Has Multiple Functions, ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex, Identification of replication factor C from Saccharomyces cerevisiae: a component of the leading-strand DNA replication complex, A close relative of the nuclear, chromosomal high-mobility group protein HMG1 in yeast mitochondria, The Role of the Human Rel Oncogene Product in Control of Transcription by the Human Immunodeficiency Virus Long-Terminal Repeat Hiv1-Ltr Kappab Elements, Replication factor-A from Saccharomyces cerevisiae is encoded by three essential genes coordinately expressed at S phase, Phosphorylation of replication protein A: A role for cdc2 kinase in G1/S regulation, Sequential initiation of lagging and leading strand synthesis by two different polymerase complexes at the SV40 DNA replication origin, The Initiation of Chromosomal DNA Replication in Eukaryotes, Functions of replication factor C and proliferating-cell nuclear antigen: functional similarity of DNA polymerase accessory proteins from human cells and bacteriophage T4, Cell-cycle-regulated phosphorylation of DNA replication factor A from human and yeast cells, Yeast replication factor-A functions in the unwinding of the SV40 origin of DNA replication, Purification and characterization of CAF-I, a human cell factor required for chromatin assembly during DNA replication in vitro, Simian virus 40 DNA replication in vitro: identification of multiple stages of initiation, Initiation of eukaryotic DNA replication in vitro, Purification of a cellular replication factor, RF-C, that is required for coordinated synthesis of leading and lagging strands during simian virus 40 DNA replication in vitro, Coordinated leading and lagging strand synthesis during SV40 DNA replication in vitro requires PCNA, Nuclear-DNA Synthesis Invitro Is Mediated Via Stable Replication Forks Assembled in a Temporally Specific Fashion In vivo, Identification of multiple cellular factors required for SV40 replication in vitro, Functional identity of proliferating cell nuclear antigen and a DNA polymerase-delta auxiliary protein, The cell-cycle regulated proliferating cell nuclear antigen is required for SV40 DNA replication in vitro, Regulation of Adenovirus Early Gene-Expression by the E1b 19k Tumor-Antigen, Regulation of Adenovirus Gene-Expression in Human Wi38 Cells by an E1b-Encoded Tumor-Antigen, Chromatin assembly during SV40 DNA replication in vitro, Characterization of Protein Which Binds Specifically to a Putative Origin of Cellular DNA-Replication. Turn your debit card on or off, set spending limits, and get alerts - all with a few quick taps! Stillman College will upgrade technology and infrastructure at Sheppard, which will be transformed into a civil rights museum and digital learning center. We take pride in providing comprehensive and creative solutions to individuals interested in building and preserving their wealth. Out of these, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. ), -2022/23, . At the heart of this mechanism is a protein that binds to start sites on the chromosomes, called the Origin Recognition Complex, ORC. CSHL Adjunct Professor Z. Josh Huang was recognized for new cell engineering tools that will have broad applications in biological research. Working with yeast and human cells, Stillman and colleagues have identified many of the cellular proteins that function at the DNA replication fork during the S phase, the portion of the cell-division cycle when DNA synthesis occurs. . 5 , . Stillman College is accredited by the Southern Association of Colleges and Schools Commission on Colleges (SACSCOC) to award baccalaureate degrees. Innovative research and educational activities never stopped during the COVID-19 pandemic. : 214. These cookies will be stored in your browser only with your consent. Home / Research / Faculty & Staff / Bruce Stillman. Structure of the active form of human Origin Recognition Complex and its ATPase motor module, Prevalent and Dynamic Binding of the Cell Cycle Checkpoint Kinase Rad53 to Gene Promoters, Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6 (vol 117, pg 17747, 2020). This cookie is set by GDPR Cookie Consent plugin. . These cookies ensure basic functionalities and security features of the website, anonymously. The cookie is used to store the user consent for the cookies in the category "Analytics". , . Stillman Bank is not responsible for the content of external web site linked to or references from the Stillman Bank web site. The Stillman lab is part of an ongoing collaboration that determined the cryo-EM structure of ORC proteins in complex with a group of proteins, called a helicase, that unwind DNA during replication. , . , , , , . Doctor of Science, (honoris causa), Clarkson University (2018), Science and Technology Award, City of Suzhou, China (2018), National Academy of Inventors, Elected Fellow (2016), Australian Academy of Science, Elected Corresponding Member (2012), Doctor of Science (honoris causa), University of Sydney (2008), Doctor of Science, (honoris causa), Long Island University (2007), Society of Surgical Oncology American Cancer Society Basic Science Award and Lecture (2006), American Association for the Advancement of Science, Elected Fellow (2005), Doctor of Science (honoris causa), Stony Brook University (2002), Doctor of Humane Letters (honoris causa), Hofstra University (2001), Doctor of Science (honoris causa), New York Institute of Technology (2001), European Molecular Biology Organization, Associate Member (2001), American Academy of Microbiology, Elected Fellow (2000), Julian Wells Medal, Lorne Genome Conference, Australia (1994), The Royal Society (London), Elected Fellow (1993). The cookie is used to store the user consent for the cookies in the category "Other. )), 37- "". Current research focuses on the mechanism that initiates the entire process of DNA replication in eukaryotic cells. 3D Printing Stillmans team has discovered that mutations in the Orc1 protein alter the ability of ORC to regulate both DNA replication and centrosome duplication. Necessary cookies are absolutely essential for the website to function properly. Adenoviral DNA replication: DNA sequences and enzymes required for initiation in vitro. 37. The cookies is used to store the user consent for the cookies in the category "Necessary". The $500,000 History of Equal Rights grant will help rehabilitate the exterior of Winsborough Hall, a former dorm that will serve as a Living and Learning Center for senior citizens. At centromeres, ORC subunits monitor the attachment of duplicated chromosomes to the mitotic spindle that pulls the chromosomes apart when they are correctly aligned. Evolution of DNA replication origin specification and gene silencing mechanisms. The cookie is used to store the user consent for the cookies in the category "Performance". Bruce Stillmans lab studies the process by which DNA is copied within cells before they divide in two. Metz Culinary Management is helping expand Stillmans Community Garden to help promote sustainability and fight food insecurity in Tuscaloosas West End. . , . Supplies can be dropped off at any one of our six office locations. One Bungtown Road, Cold Spring Harbor, NY 11724, Sitemap | Privacy Policy | Web Accessibility, Our website uses cookies to enhance your experience on the site. )), : "", . Stillman Bank web site neither endorses the information, content, presentation, or accuracy nor makes any warranty, expressed or implied, regarding these external web sites. With your Stillman Bank Debit Card, you have access to 37,000+ ATMs across the nation with MoneyPass! "" LHF, : - , - , , , ? , . Open a checking account, savings acouunt, or CD online from the comfort of your home! , , , . The twentieth annual Womens Partnership for Science lecture and luncheon was held to support, promote, and celebrate women researchers at CSHL. No matter what type of home loan you're looking for, we have the financing solutions to fit your needs! The human Origin Recognition Complex is essential for pre-RC assembly, mitosis and maintenance of nuclear structure. We also use third-party cookies that help us analyze and understand how you use this website. , : "" , . That is why we've designed a wide variety of checking and savings account options for you to choose from. We offer the products and services you expect from big banks, but we do it with a friendly, hometown touch. You also have the option to opt-out of these cookies. Cyclin binding Cy motifs have multiple activities in the initiation of DNA replication, A structural view of the initiators for chromosome replication, Histone Modifications: Insights into Their Influence on Gene Expression, The dNTP triphosphohydrolase activity of SAMHD1 persists during S-phase when the enzyme is phosphorylated at T592, Cryo-EM structure of Mcm2-7 double hexamer on DNA suggests a lagging-strand DNA extrusion model, Structural basis of Mcm2-7 replicative helicase loading by ORC-Cdc6 and Cdt1, Key mechanism in the loading and activation of the replicative helicase MCM2-7, Opposing roles for DNA replication initiator proteins ORC1 and CDC6 in control of Cyclin E gene transcription, Targeted Doxorubicin Delivery to Brain Tumors via Minicells: Proof of Principle Using Dogs with Spontaneously Occurring Tumors as a Model, Concerted activities of Mcm4, Sld3 and Dbf4 in control of origin activation and DNA replication fork progression, Reconsidering DNA Polymerases at the Replication Fork in Eukaryotes, Orc1 Binding to Mitotic Chromosomes Precedes Spatial Patterning During G1 Phase and Assembly of the Origin Recognition Complex in Human Cells, Rhabdomyosarcoma: Current Challenges and Their Implications for Developing Therapies, Structural and mechanistic insights into Mcm2-7 double-hexamer assembly and function, Acquired Dependence of Acute Myeloid Leukemia on the DEAD-Box RNA Helicase DDX5, Domain within the helicase subunit Mcm4 integrates multiple kinase signals to control DNA replication initiation and fork progression, Deoxynucleoside triphosphate (dNTP) synthesis and destruction regulate the replication of both cell and virus genomes, Cryo-EM structure of a helicase loading intermediate containing ORC-Cdc6-Cdt1-MCM2-7 bound to DNA, Immunoblotting histones from yeast whole-cell protein extracts, Principles and concepts of DNA replication in bacteria, archaea, and eukarya, In vitro reconstitution of budding yeast pre-RC, competent in recruitment of recombinant pre-IC components, using purified, recombinant proteins, DDX5 regulates DNA replication and is required for cell proliferation in a subset of breast cancer cells, Meier-Gorlin syndrome mutations disrupt an Orc1 CDK inhibitory domain and cause centrosome reduplication, The origin recognition complex: a biochemical and structural view, Cdc6-Induced Conformational Changes in ORC Bound to Origin DNA Revealed by Cryo-Electron Microscopy, Partial MCM4 deficiency in patients with growth retardation, adrenal insufficiency, and natural killer cell deficiency, Replication-coupled chromatin assembly generates a neuronal bilateral asymmetry in C. elegans, Phosphorylation of H4 Ser 47 promotes HIRA-mediated nucleosome assembly, Reversible suppression of an essential gene in adult mice using transgenic RNA interference, A Common Telomeric Gene Silencing Assay Is Affected by Nucleotide Metabolism, An analysis of CAF-1 interacting proteins reveals dynamic and direct interactions with the ku complex and 14-3-3 proteins, Human origin recognition complex is essential for HP1 binding to chromatin and heterochromatin organization, Break-induced replication requires all essential DNA replication factors except those specific for pre-RC assembly, Deciphering protein kinase specificity through large-scale analysis of yeast phosphorylation site motifs, The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4, A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication, The elongator complex interacts with PCNA and modulates transcriptional silencing and sensitivity to DNA damage agents, Sequential treatment of drug-resistant tumors with targeted minicells containing siRNA or a cytotoxic drug, A proposal for a coordinated effort for the determination of brainwide neuroanatomical connectivity in model organisms at a mesoscopic scale, Orc1 Controls Centriole and Centrosome Copy Number in Human Cells, ABF1-binding Sites Promote Efficient Global Genome Nucleotide Excision Repair, The architecture of the DNA replication origin recognition complex in Saccharomyces cerevisiae, DNA polymerases at the replication fork in eukaryotes, ATP dependent assembly of the human origin recognition complex, Initiation of DNA replication - Assembly of a molecular machine depends on origin DNA, Bacterially derived 400 nm particles for encapsulation and cancer cell targeting of chemotherapeutics, Cdc6 ATPase activity regulates ORC center dot Cdc6 stability and the selection of specific DNA sequences as origins of DNA replication, Constitutively high dNTP concentration inhibits cell cycle progression and the DNA damage checkpoint in yeast Saccharomyces cerevisiae, Cdc7-Dbf4 phosphorylates MCM proteins via a docking site-mediated mechanism to promote S phase progression, Support for the Human Cancer Genome Project, ATPase-dependent cooperative binding of ORC and Cdc6 to origin DNA, Structural basis for origin recognition complex 1 protein-silence information regulator 1 protein interaction in epigenetic silencing, Human Orc2 localizes to centrosomes, centromeres and heterochromatin during chromosome inheritance (vol 23, pg 2651, 2004), Origin recognition and the chromosome cycle, Human Orc2 localizes to centrosomes, centromeres and heterochromatin during chromosome inheritance, Deregulation of cyclin E in human cells interferes with prereplication complex assembly, Dynamics of pre-replication complex proteins during the cell division cycle, Perpetuating the double helix: molecular machines at eukaryotic DNA replication origins, Biochemical characterization of DNA damage checkpoint complexes: Clamp loader and clamp complexes with specificity for 5' recessed DNA, Chromatin assembly factor 1 is essential and couples chromatin assembly to DNA replication in vivo, Structure and function of the BAH-containing domain of Orc1p in epigenetic silencing, Orc6 involved in DNA replication, chromosome segregation, and cytokinesis, Yph1p, an ORC-interacting protein: Potential links between cell proliferation control, DNA replication, and ribosome biogenesis, Functions of sensor 1 and sensor 2 regions of Saccharomyces cerevisiae Cdc6p in vivo and in vitro, Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication, DNA replication - Genomic views of genome duplication, Binding of cyclin-dependent kinases to ORC and Cdc6p regulates the chromosome replication cycle, Opening of the clamp: An intimate view of an ATP-driven biological machine, Human-Saccharomyces cerevisiae proliferating cell nuclear antigen hybrids - Oligomeric structure and functional characterization using in vitro DNA replication, FASCIATA genes for chromatin assembly factor-1 in Arabidopsis maintain the cellular organization of apical meristems, Chromatin association of human origin recognition complex, Cdc6, and minichromosome maintenance proteins during the cell cycle: Assembly of prereplication complexes in late mitosis, PCNA connects DNA replication to epigenetic inheritance in yeast, The N-terminal domains of histones H3 and H4 are not necessary for chromatin assembly factor-1-mediated nucleosome assembly onto replicated DNA in vitro, Cdc6p modulates the structure and DNA binding activity of the origin recognition complex in vitro.